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We are excited to introduce our latest product: 
-The HYE Species Mix-
a meticulously crafted reference mix designed to optimize mass spectrometry applications.



Application areas of the HYE Species Mix:

Routine MS Quality Control (QC)

Ensure the reliability and consistency of your mass spectrometry results with our reference mix, tailored for routine quality control procedures.

Sensitivity and Dynamic Range Checks

Effectively evaluate the sensitivity and dynamic range of your mass spectrometry systems, allowing for optimal method performance and detection capabilities.


MS Device Benchmarking

Utilize the Species Mix to benchmark your mass spectrometry devices, providing a standard reference for performance comparison and validation.



MS Method Development

Streamline your method development process with our reference mix, facilitating the optimization of protocols and enhancing analytical outcomes.

 Quality Assurance for Sample Preparation

 Use the Species Mix as a control to ensure that sample preparation techniques, such as digestion and purification, are performed accurately and yield consistent results.

 Reproducibility Testing

 Assess the reproducibility of your mass spectrometry analyses by repeatedly testing with the Species Mix to confirm consistent performance over time.


Structure of the HYE Species Mix

Our HYE-Mix consists of a carefully balanced blend of species-specific peptide extracts and contains two components to meet the varying requirements of your experiments:


HYE-Mix A: Contains 65% human protein, 30% yeast protein, and 5% E. coli protein.

    

HYE-Mix B: Contains 65% human protein, 15% yeast protein, and 20% E. coli protein.


Both mixtures provide an ideal foundation for a variety of mass spectrometric applications. The balanced protein distribution enables precise analyses and helps you achieve reliable results—whether in sensitivity testing, the development of MS methods, or the quality assurance of your sample preparation.


Select individual mix

Combine both mixes


LC/MS Performance

Our protein reference extracts are the ideal solution for reliably monitoring the performance of your mass spectrometer:


     Consistent peptide retention times as well as                           stable signal intensities

    Reproducible protein ratios through targeted mixing            of HYE Species Mix A and B with a maximum deviation          of less than 5% (Top 20 of the most common proteins):

​(i) Saccharomyces cerivisiae ​1:2

​(ii) Homo sapiens ​1:1

​(iii) Escherichia coli 1:4